Whilst low-count MBL almost never progresses to CLL, significant-count MBL progresses to CLL demanding therapy in a charge of one% to 2% every year. Large-rely MBL is distinguished from Rai 0 CLL based upon whether or not the B-cell rely is previously mentioned or under five × 109/L. Whilst folks with both large-rely MBL and CLL Rai phase 0 are at